Juliana Sofia Machado Simões

ESR 3 - Juliana Sofia Machado Simões

 

 

 

PERSONAL INFORMATION

 

Gender: Female

Contry of Birth: Portugal

MSc in: Biomedical Sciences

University College of London

 
 
MARIE SKLODOWSKA CURIE PhD FELLOWSHIP

To define effect of oxysterols on mammalian sperm functionality, membrane remodelling, mitochondrial function, oxidative stress, DNA integrity, and fertilization ability using either an in silico (biological networks-based computational modelling) or in vitro approach (flow cytometry, 2D electrophoresis, HPLC, mass spectrometry, confocal microscopy, IVF)

 
 
 
 
PROJECT TITLE

Effect Of Dietary On Mammalian Spermatozoa Membrane Lipid Remodelling.

 
 
 
 
SUPERVISOR and TUTORS

 

Internal tutor

 

 

 
 
 
 
OBJECTIVES

 

  • Clarify the effect of diet on mammalian sperm function. In particular on sperm membrane capacitation-dependent remodeling.

 

  • Design innovative strategies aimed to control in vivo and in vitro this process.
 
 
 
 
EXPECTED RESULTS
  • Define the role of cholesterol and oxysterols in boar sperm capacitation.

 

  • Understand the role of ROS in oxysterols’ formation and sperm capacitation.

 

  • Apply new methods to the study of sperm membrane remodeling.

 

  • Elucidate the effect of diet on boar sperm function.
 
 
 
 
PLANNED SECONDMENT
  • University of Padova

 

  • Center for Neuroscience and Cell Biology-University of Coimbra

 

  • Laboratorio di analisi Dr Fioroni s.r.l.
 
 
 
 
CURIOSITY
D: Why and what do you like about Teramo?
R: I like that Teramo is a small city, making it easier to get to know other people and making us feel at home.
 
D: What is your favourite food local dish/food?
R: My favorite local food is the traditional Arrosticini
 
 
 

Rep-Eat - H2020-MSCA-COFUND-2015

University of Teramo - Via Renato Balzarini 1 - 64100 - Teramo (TE) - Italy

repeat@unite.it  - Private Area

 
 
 
Flag UE

This project has received funding from the European Union’s Horizon 2020 

research and innovation programme under 

the Marie Skłodowska-Curie grant agreement No 713714

 

 

Co-funding institutions