The 12th Annual Meeting of the International Conference on Genomics (the ICG-12) hosted by BGI-Shenzhen will be held from Thursday, October 26 to Sunday, October 29, in the China National GeneBank, Dapeng District, Shenzhen. As an international conference with significant impact on the 'omics' field, the ICG is a collaborative community for scientific experts and scholars from all over the world, as well as for entrepreneurs in related fields. Following the theme "Omics for All" and the vision of trans-omics for a better life, ICG-12 will focus on recent breakthroughs and offer an open intellectual environment where multi-faceted thinking can blossom. With the first anniversary of China National GeneBank (CNGB), the prospect of new high-throughput sequencing systems in BGI, and the significant achievements of the Synthetic Yeast Genome Project, we hope that more people will join us in promoting sustainable development in omics, and in paying close attention to the growth of cutting-edge technology.