REP-EAT

Objectives: to study the interaction of food quality and of food-related pathologies on reproduction

 
 
 
 
 
 
 

Gene-Environment interactions in Eating Disorders and Obesity and their relationship with the reproductive functioning

ERS 06

Objectives, methods and topic interactions:

  • To evaluate the significance of epigenetic mechanisms in the progression of Eating Disorders (ED) and obesity in different animal models of the diseases (KI, UniCam, nuben);
  • To evaluate the effects of nutrients with known epigenetic activity for their ability to control these diseases and body weight gain in animal models;
  • To assess how ED and obesity are related to reproductive health (UD’A). This will be achieved by the interaction with ESR3;
  • To investigate if specific alterations of gut microbiota may lead to behavioural as well as epigenetic modulation in the different diseases under study. This will be achieved by the interaction with ESR7;
  • To provide the ESR with essential neurobiological information of ED and Obesity in the attempt to train him/her for future design and execution of research projects.
 

Evaluation of endocrine disruptors effects in animal models and their impact on consumer

ERS 08

Objectives, methods and topic interactions:

  • To investigate the marine food chain pollution in Abruzzi (Bussi-Tirino) and identification of pollutants of toxicological relevance in samples of marine organisms (URV). This activity will be carry out in a specialized research center in the area of Technology Transfer in Toxicology, Food and Environmental Health by using the use of most sophisticated instruments (LC-MS, GC-MS, HPLC)(ISS, IPMA).
  • To identify the effects of climate change to marine organisms (using farmed meagre and mussels as models) in contaminated environments and assess the potential risks for consumers (IPMA) using specific software as Geographic Information Systems (GIS) or ArcGIS.
  • To verify the toxic effect of detected pollutants on neuroendocrine, reproductive efficiency, fetal malformations and reproductive tumor development in the zebrafish model; In this phase it is envisaged an interaction with ESR3, ESR7 and ESR11.
 

Valorisation of alternative, healthier and environmental compatible food production chain relying on typical sheep breeds in Abruzzo Region

ERS 12

Internal Tutor

Pasqualino Loi

 

External academic instiution

University of Sheffield

 

Tutor

Alireza Fazeli

 

Non-academic institution

Avantea s.r.l. Laboratorio di Tecnologia della riproduzione

 

Supervisor

Cesare Galli 

 

Objectives, methods and topic interactions:

  • To establish the genetic backgrounds of the remaining heads of Pagliarola breed;
  • To learn in vitro and in vivo (in situ) approaches (In Vitro embryo Production , Ovum Pick Up and Embryo Transfer ) to amplify the reproductive performances of Abruzzi sheep breeds (Pagliarola breed);
  • To explore nutritional strategies to improve cryo tolerance of ram spermatozoa through interaction with ESR 2 & 4.
  • To gain expertise on IVP & OPU-ET on a broader panel of animals species and to explore commercial opportunities outside the academia (Avantea);
  • To get acquainted with the embryological procedures applied to farm animals in a leading EU embryological laboratory (TUOS);
  • To explore the interest of the reexpansion of typical breed in an organic farming context, for the production of organic meat.
 

 

Rep-Eat - H2020-MSCA-COFUND-2015

University of Teramo - Via Renato Balzarini 1 - 64100 - Teramo (TE) - Italy

repeat@unite.it  -  Private Area

 
Flag UE

This project has received funding from the European Union’s Horizon 2020 

research and innovation programme under 

the Marie Skłodowska-Curie grant agreement No 713714

 

 

Co-funding institutions