To evaluate the significance of epigenetic mechanisms in the progression of Eating Disorders (ED) and obesity in different animal models of the diseases (KI, UniCam, nuben);

To evaluate the effects of nutrients with known epigenetic activity for their ability to control these diseases and body weight gain in animal models;

To assess how ED and obesity are related to reproductive health (UD’A). This will be achieved by the interaction with ESR3;

To investigate if specific alterations of gut microbiota may lead to behavioural as well as epigenetic modulation in the different diseases under study. This will be achieved by the interaction with ESR7;

To provide the ESR with essential neurobiological information of ED and Obesity in the attempt to train him/her for future design and execution of research projects.

ESR 12

Valorisation of alternative, healthier and environmental compatible food production chain relying on typical sheep breeds in Abruzzo Region

Internal Tutor

Pasqualino Loi

External academic instiution

University of Sheffield

Tutor

Alireza Fazeli

Non-academic institution

Avantea s.r.l. Laboratorio di Tecnologia della riproduzione

Supervisor

Cesare Galli

ESRs

Yosra Ressaissi

Objectives, methods and topic interactions:

To establish the genetic backgrounds of the remaining heads of Pagliarola breed;

To learn in vitro and in vivo (in situ) approaches (In Vitro embryo Production , Ovum Pick Up and Embryo Transfer ) to amplify the reproductive performances of Abruzzi sheep breeds (Pagliarola breed);

To explore nutritional strategies to improve cryo tolerance of ram spermatozoa through interaction with ESR 2 & 4.

To gain expertise on IVP & OPU-ET on a broader panel of animals species and to explore commercial opportunities outside the academia (Avantea);

To get acquainted with the embryological procedures applied to farm animals in a leading EU embryological laboratory (TUOS);

To explore the interest of the reexpansion of typical breed in an organic farming context, for the production of organic meat.

Rep-Eat - H2020-MSCA-COFUND-2015

University of Teramo - Via Renato Balzarini 1 - 64100 - Teramo (TE) - Italy

repeat@unite.it - Private Area

REP_EAT MSCA Co-funding of regional, national and international programmes (COFUND) HORIZON 2020” – Grant Agreement N. 713714.CUP: C47B16000360007

University of Teramo

Abruzzo Region